An Israeli military spokeswoman said Israel does not comment on foreign reports.
During the more than seven-year conflict in neighbouring Syria, Israel has grown deeply alarmed by the expanding clout of its arch enemy Iran – a key ally of Syrian President Bashar al-Assad.
Israel’s air force has struck scores of targets it describes as Iranian deployments or arms transfers to Lebanon’s Iran-backed Hezbollah movement in the war.
“Our air defence systems thwarted an Israeli missile aggression on Damascus International Airport,” Syrian state news agency SANA cited a military source as saying.
Witnesses at a major trade fair in the capital Damascus said they saw flares shooting up into the night sky.